BPC-157

A pentadecapeptide derived from human gastric juice with remarkable tissue healing properties across tendons, muscles, nerves, and the GI tract.

Normal Protocol

Advanced Protocol

Overview

Also Known As

Body Protection Compound-157, PL 14736, PL-10, Bepecin

Mechanism of Action

Upregulates growth factor expression (EGF, VEGF, FGF), modulates nitric oxide system, promotes angiogenesis and tendon fibroblast growth, interacts with dopamine and serotonin systems

Product

Body Protection Compound-157, PL 14736, PL-10, Bepecin vial
Dosing & Administration
Typical protocols and routes

Half-Life

Stable in gastric juice; estimated biological half-life of several hours

Administration Routes

subcutaneousoralintramuscular

Dosing Protocols

Average: 0.5 mg/day (vial lasts 20 days) — reconstitute 10 mg vial with 1 mL bacteriostatic water, draw 10 units on insulin syringe (marked 1-100). Advanced: 1 mg/day (vial lasts 10 days) — reconstitute 10 mg vial with 1 mL bacteriostatic water, draw 10 units on insulin syringe.
Research
Key findings and status

Key Research Findings

Shown to accelerate healing of transected Achilles tendon, medial collateral ligament, and quadriceps muscle in rat models. Demonstrated gastroprotective effects comparable to standard antiulcer agents. Shown neuroprotective effects in models of traumatic brain injury.
Detailed Information

BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protein found in human gastric juice. It has demonstrated remarkable healing properties across multiple tissue types in preclinical research, including tendons, ligaments, muscles, the nervous system, and the gastrointestinal tract.

Overview

BPC-157 is a pentadecapeptide composed of 15 amino acids. It is derived from a portion of the body protection compound (BPC) found naturally in human gastric juice. Unlike many peptides, BPC-157 is stable in human gastric juice and does not need carrier agents for bioactivity.

Research Highlights

Preclinical studies have shown BPC-157 accelerates the healing of various wound types including transected tendons, damaged ligaments, crushed muscles, and bone fractures. It also demonstrates cytoprotective and antiulcer activity systemically and when administered locally.

Safety & Legal

Side Effects & Warnings

Generally well-tolerated in preclinical studies. No significant toxicity observed at standard research doses. Limited human safety data available.

Legal Status

Research use only
Molecular Data
Chemical properties

Molecular Weight

1419.53 g/mol

Amino Acid Sequence

Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Quick Facts

Class

BPC

Research Status

Preclinical

Half-Life

Stable in gastric juice; estimated biological half-life of several hours

Routes

subcutaneous
oral
intramuscular

Category

Healing & Recovery